Probe Rush — 60-Second FISH Nomenclature Challenge

Probe Rush is a free, browser-based speed game that tests your ability to read FISH probe signal patterns and pick the correct ISCN nomenclature. You get 60 seconds. Every answer auto-submits the moment you tap it, so fast correct picks earn the biggest bonuses.

How it works

  • Tier 1 (questions 1–5): enumeration probes — single, dual-color deletion panels (del(5q), del(7q), del(20q), del(13q14), del(17p)), and tri-color panels like the CLL ATM/TP53/CEP12 set and the MDS EGR1/D7S486/CEP8 set.
  • Tier 2 (6–15): break-apart, dual-fusion, and single-fusion probes mixed in.
  • Tier 3 (16+): hard atypical patterns — amplifications, cryptics, complex tri-color combos.

Built for cytogenetics

Probe Rush is one of several free FISH and cytogenetics tools on CruxSci, alongside the Probe Nomenclature Game, CytoScoper chromosome ID game, and Karyotype Visualizer.